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This depends entirely on cause

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Organic sources include amino acids, beef extract, hydrolyzed proteins, tryptic soy broth, malt extract, yeast extract, and urea

Modulation of transport activity is potentially a way to control intracellular ascorbate status in mammalian cells since, even in those species able to synthesise it, it is distributed from its main site of synthesis in the liver

Nitrate-regulated glutaredoxins control Arabidopsis primary root growth